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When John Keats - a young, struggling poet - moves to Hampstead with his friend Charles Brown he falls under the spell of his landlady's beautiful, spirited daughter Fanny Brawne. As the sensitive though sickly Keats falls in love with the forthright and flirtatious girl the two become aware that they could never hope to marry on his meagre income and so, when he becomes gravely ill and is sent to spend the winter in the restorative climate of Rome she has no choice but to stay behind in England.